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Tracheobronchial Amyloidosis

Imaging findings

CT shows irregular, multifocal tracheal narrowing with mucosal thickening and calcified submucosal plaques/nodules along both the cartilaginous walls and the posterior membranous sheath, representing tracheobronchial amyloidosis.

Key takeaways

Tracheobronchial amyloidosis is a localized deposition of amyloid protein in the airway walls. Uniquely, it involves both the anterior cartilaginous rings and the posterior membranous trachea, helping to differentiate it from tracheobronchopathia osteoplastica or relapsing polychondritis.

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