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Bilateral Primary Pulmonary Adenocarcinomas (Bubbly Lung Lesions)

Bilateral Primary Pulmonary Adenocarcinomas (Bubbly Lung Lesions)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Serial chest CTS and MRIs over several years show slow progression of two bilateral, bubbly, soft-tissue lesions with central lucencies in both lower lobes. Biopsy of the right lower lobe lesion confirmed primary pulmonary adenocarcinoma.

Key takeaways

Primary pulmonary adenocarcinomas, particularly those with a lepidic growth component (formerly bronchioloalveolar carcinoma or BAC), classically present as slowly growing, "bubbly" or pseudocystic ground-glass nodules with central lucencies. These lesions can be bilateral or multifocal and are frequently misdiagnosed as focal scars or atelectasis on serial imaging.

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