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Metastatic Renal Cell Carcinoma (RCC) Presenting as Bone and Lung Metastases

Metastatic Renal Cell Carcinoma (RCC) Presenting as Bone and Lung Metastases▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Cervical spine and chest CT images reveal extensive destruction and near-complete absence of the C3 vertebral body, along with multiple other lytic lesions throughout the spine and a lytic lesion in the humerus. Inumerable pulmonary nodules of varying sizes are scattered throughout the lungs. Abdominal CT confirms a large, partially calcified primary mass in the right kidney.

Key takeaways

Renal cell carcinoma is notorious for presenting with distant metastases at the time of initial diagnosis in up to one-third of patients. The skeletal metastases are typically highly destructive, purely lytic, and hypervascular, frequently involving the spine and appendicular skeleton, and are often accompanied by hematogenous pulmonary metastases.

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