CTICasesMetastatic Pulmonary Calcification
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Imaging findings
Dual-energy chest radiograph and high-resolution chest CT show upper-lobe-predominant centrilobular ground-glass nodules that spare the periphery of the secondary pulmonary lobules (asinar pattern). Bone scintigraphy demonstrates intense, diffuse uptake of the radiotracer within the upper lung zones, confirming the presence of metastatic calcium deposits in a patient with chronic renal failure.
Key takeaways
Metastatic pulmonary calcification is a systemic deposition disorder occurring in patients with chronic renal failure and secondary hyperparathyroidism. The CT findings of centrilobular ground-glass or air-space nodules can mimic infection, edema, or hemorrhage; however, intense tracer uptake on a bone scan is diagnostic and diagnostic of dystrophic/metastatic calcium deposition.
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