CTICasesLymphomatoid Granulomatosis with Pulmonary and Dermal Manifestations
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Imaging findings
Initial CT showed extensive inflammatory edema and discrete nodular opacities in the abdominal wall. In the lower lungs, multiple nodules were observed, including a large non-segmental opacity in the right lower lobe and a cavitary lesion. Follow-up PET scan showed widespread metabolic activity in these lesions. Biopsy of abdominal wall soft tissues and transbronchial biopsy were consistent with EBV-positive lymphomatoid granulomatosis.
Key takeaways
Lymphomatoid granulomatosis is an EBV-positive lymphoproliferative disorder that can affect both the lungs and skin, and sometimes the CNS. Pulmonary manifestations include cavitary nodules, often large and widespread. The skin presentation can involve extensive dermal and subcutaneous abnormalities. It is primarily a B-cell tumor, often with many T-cells.
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